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Testosterone “does not increase risk of heart attack”


Although some research has linked testosterone therapy with an increased risk of stroke and heart attack, a new study involving over 25,000 older men says otherwise. Testosterone prescriptions for older men are not as common in UK as in US. In the United States it is as normal as paracetamol prescription for your headache bringing nearly $1.6 billion profit each year. More energy, more strength, better sex, less anxiety, better mood, more muscle, less fat and more focus. Quite tempting, especially if you have a few miles on, and as long as it’s safe for us, I guess none of us would mind that feeling of being young again.


Testosterone Research

The study, conducted by researchers at the University of Texas Medical Branch at Galveston revealed number of inconsistencies and conflicting results in previous studies. The study found that risk could double for men over 65 or users who were younger than 65 but had a history of heart disease. No such effect was noticed for men under 65 years of age without a history of heart disease, the researchers said. To further explore this issue, UTMB team examined data gathered on more than 25,000 men over the age of 65. The findings in studies of the Medicare beneficiaries (July 2 “Annals of Pharmacotherapy”) who received testosterone therapy for up to eight years, concluded that testosterone therapy was not linked with an increased risk for heart attack. In fact it was found that men at greater risk for heart problem actually had a lower rate of heart attacks than similar men who did not receive testosterone therapy, the researchers said. In other research the authors of article published in December 2013 in the esteemed Journal of the American Heart Association, reviewed well over 100 studies with the goal of providing a comprehensive review of the clinical literature that has examined the associations between cardiovascular disease and testosterone. Findings revealed that low levels of testosterone contribute to higher rates of mortality, obesity, diabetes and cardiovascular- related mortality. Testosterone therapy has been shown to lower body mass index in obese patients, lower blood sugar in diabetics. It has also shown that lower testosterone levels contributed to thickening walls of some of the major blood vessels which increases the risk of atherosclerosis. All of these factors bring to a conclusion that optimal testosterone levels decrease the risk of cardiovascular disease.



Many of these research indicate that Testosterone Therapy can be a great way to help men enhance their quality of life and decrease their risk of many diseases. Importantly though, we can not disregard possible risks and should never undertake it lightly. Testosterone replacement should always be properly monitored by a hormone specialist that is well versed in the risks of therapy. Always test your blood cell counts and estrogen levels on testosterone therapy to assess the risk factors for cardiovascular disease. Doctors should be educated here and know when the risks outweigh the benefits. Despite these and other findings did not show any link between increased risk of heart attack and testosterone use in older men, this issue is still far from being settled and will probably need “Large scale, randomized clinical trials” to provide more definitive evidence.

References Jacques Baillargeon et al. Risk of Myocardial Infarction in Older Men Receiving Testosterone Therapy. Annals of Pharmacotherapy. July 2014 DOI: 10.1177/1060028014539918

July 9, 2014 |

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